Methods for detecting at least one mutation in a plurality of cancer-related genes, selecting an individual for treatment and predicting the likelihood of responsiveness to treatment.

摘要

The present technology relates to methods for determining whether a patient diagnosed with breast cancer, colorectal cancer, melanoma or lung cancer will benefit from or is expected to be responsive to treatment with an individual therapeutic agent or a specific combination of agents. Therapeutic These methods are based on screening the patient's solid tumors and detecting changes in target nucleic acid sequences corresponding to a specific set of cancer-related genes. Kits are also provided for use in the practice of the methods.