Methods for detecting at least one mutation in a plurality of thyroid cancer-related genes, for selecting a subject that has thyroid nodules, and for predicting risk of malignancy, and, kit.

摘要

The present technology relates to methods for determining whether a patient who has undetermined cytological thyroid nodules will benefit from diagnostic surgery, for example, lobectomy. These methods are based on screening a patient's thyroid nodules and detecting changes in target nucleic acid sequences that correspond to a specific set of thyroid cancer-related genes. Kits are also provided for use in performing the methods.