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Large nuclei specially designed to detect the genomic sequence of hepatitis B virus.

机译:专为检测乙型肝炎病毒的基因组序列而设计的大核。

摘要

The present invention relates to giant nucleons designed to recognize and isolate a recognition sequence within an open reading framework of at least two genetic viruses.Hepatitis B (VHB).Current inventions also include the use of this designed super-large Nucleon in pharmaceutical ingredients and the treatment or reduction of symptoms of VHB infection.Or treat hepatocellular carcinoma (CHC).In addition, the invention also includes pharmaceutical ingredients consisting of genetically engineered giant nuclear proteins.The designed giant nucleoside-coded nucleic acids and the use of these components in the treatment of VHB or CHC infections.
机译:本发明涉及设计用于识别和分离至少两种遗传病毒的开放阅读框架内的识别序列的巨大核子。乙型肝炎(VHB)。本发明还包括这种设计的超大核子在药物成分和药物中的用途。或治疗肝细胞癌(CHC)。此外,本发明还包括由基因工程巨核蛋白组成的药物成分。设计的巨核苷编码核酸以及这些成分的用途VHB或CHC感染的治疗。

著录项

  • 公开/公告号CO2019003675A2

    专利类型

  • 公开/公告日2019-04-30

    原文格式PDF

  • 申请/专利权人 PRECISION BIOSCIENCES INC.;

    申请/专利号CO20190003675

  • 发明设计人 SMITH JAMES JEFFERSON;JANTZ DEREK;

    申请日2019-04-12

  • 分类号C12N9/22;A61K38;

  • 国家 CO

  • 入库时间 2022-08-21 12:02:51

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