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Builders of biespecÍficos Antibodies that bind to t Cells

机译:绑定至t细胞的biespecÍficos抗体的制造商

摘要

The present Invention provides constructs a Modality specific Antibody biespecíficos FC characterized because they include a First Domain that binds to a surface antigen of a célEd Diana, a Second Domain that binds to an extracellular epitope of the cd3e Chain of Human and Macaca and / or a Third Domain, which is the specific mode FC.Further, The Invention provides a polinucleótido Antibody, which encodes the Construct, a Vector comprising this polinucleótido, host cells.Expressing the Construct, and a Pharmaceutical composition comprising the same.
机译:本发明提供了一种构建物形式特异性抗体biespecíficosFC的构建物,其特征在于它们包括与细胞的表面抗原结合的第一结构域,与人和猕猴的cd3e链的胞外表位结合的第二结构域和/或第三域,其是特定模式FC。进一步,本发明提供了编码该构建体的多核糖核酸抗体,包含该多聚核糖核酸的载体,表达该构建体的宿主细胞以及包含该构建体的药物组合物。

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