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Heterodimeric immunoglobulin constructs and preparation methods thereof
Heterodimeric immunoglobulin constructs and preparation methods thereof
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机译:异二聚体免疫球蛋白构建体及其制备方法
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摘要
The present invention provides a method for production of stable and highly specific heterodimeric immunoglobulin constructs, e.g., bispecific antibodies, retaining desirable properties of native IgG and lacking undesirable heavy chain-light chain mispairing, that can simultaneously bind two target molecules and are more potent in the treatment of complex diseases.
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