首页> 外国专利> Use of N-cyclohexyl-2-1-(pyridin-2-yl)ethylidenehydrazinecarbothioamide as an inhibitor of reproduction of gram-positive microorganisms and Candida albicans fungi

Use of N-cyclohexyl-2-1-(pyridin-2-yl)ethylidenehydrazinecarbothioamide as an inhibitor of reproduction of gram-positive microorganisms and Candida albicans fungi

机译:N-环己基-2- [1-(吡啶-2-基)亚乙基]肼甲硫代酰胺用作革兰氏阳性微生物和白色念珠菌真菌繁殖的抑制剂

摘要

The invention relates to chemistry and medicine, in particular to the use of a compound of the class of thiosemicarbazones, which exhibits high antimicrobial and antifungal activity, and can find application in medicine and veterinary medicine as an antimicrobial and antifungal drug or ingredient in creating selective nutrient media for growing microorganisms and fungi.Summary of the invention consists in the use of N-cyclohexyl-2-[1-(pyridin-2-yl)ethylidene]hydrazinecarbothioamide of the formula:as an inhibitor of reproduction of gram-positive microorganisms and Candida albicans fungi.The result of the invention consists in increasing the bacteriostatic and bactericidal activity against gram-positive microorganisms Staphylococcus aureus, Bacillus cereus, Enterococcus faecalis 2…12 times and in providing high antifungal activity against Candida albicans fungi.
机译:本发明涉及化学和医学,特别是涉及具有高抗微生物和抗真菌活性的硫代半咔唑类化合物的用途,并且可以作为抗微生物和抗真菌药物或成分在药物和兽医学中应用,以产生选择性。本发明的概述在于使用下式的N-环己基-2- [1-(吡啶-2-基)亚乙基]肼基碳硫磺酰胺作为革兰氏阳性微生物繁殖的抑制剂本发明的结果在于增加了对革兰氏阳性微生物金黄色葡萄球菌,蜡状芽孢杆菌,粪肠球菌的抑菌和杀菌活性2…12倍,并且提供了对白色念珠菌的高抗真菌活性。

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