A formulation of Drug delayed release

摘要

Claim 1: Drug slow release Formulation for oral Administration for Administering a drug to the colon of a subject, comprising that: a Core and a Coating Formulation for the core, the core comprising a Drug and understanding the non St , an external layer and an internal layer.Where the outer layer comprising a mixture of a First Polymer Material which is susceptible to attack by bacteria in the colon, and a Second polymeric material that has a pH Threshold of approximately pH 5 or higher, where the Inner Layer comprises a Third Polymer Material It is Soluble in intestinal Fluid or gastrointestinal Fluid,And a third group of said polymeric material is a Polymer policarboxu00edlico acid is at least partially neutralized and a nonionic Polymer, provided that, when said Third polymeric material is a nonionic Polymer, comprising the Inner Layer At least one Additive selected from a buffering Agent and a base.