DECREASING EXPRESSION LEVEL OF PROTEASOME SUBUNIT GENES BY TREATING A HUMAN SUBJECT WITH A NITROXIDE

摘要

Some embodiments disclosed herein include a method for decreasing gene expression of a gene. The methods can include identifying a human subject over the age of 35 and having an increase expression level of a gene associated with proteasome activity; and administering to the human subject an effective amount of a nitroxide antioxidant, whereby expression level of the gene is decreased.