ANTIGEN-SURFACE-COUPLED LIPOSOME VACCINE FOR NON-HUMAN ANIMALS

摘要

Disclosed is a vaccine for non-human animals, which can effectively induce immunity in a non-human animal such as a farm animal and a poultry. The vaccine for non-human animals according to the present invention contains a liposome having, coupled to the surface thereof, an antigen molecule derived from a pathogen capable of affecting a non-human animal. The non-human animal is, for example, a farm animal or a poultry. An infectious bronchitis virus (IBV) vaccine, which is one of the most preferred embodiments of the vaccine of the present invention, is effective against various isolated IBV strains, and is expected to be sufficiently available in the case where a mutant strain occurs. A PRRSV vaccine, which is another preferred embodiment of the vaccine of the present invention, is confirmed to have an effect to alleviate fever due to an infection or reduce the formation of a lesion in the lung and the like. According to the present invention, it becomes possible to develop a liposome vaccine effective for the prevention of infections with pathogens for various non-human animals, such as IBV and PRRSV.