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RGD Biphenyl-containing RGD derivatives a process for the preparation thereof and a radiopharmaceuticals comprising the same
RGD Biphenyl-containing RGD derivatives a process for the preparation thereof and a radiopharmaceuticals comprising the same
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机译:RGD含联苯的RGD衍生物,其制备方法和包括该衍生物的放射性药物
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摘要
According to one aspect of the present invention, provided is a compound represented by chemical formula I, having a structure in which a tumor-selective arginylglycylaspartic acid (Arg-Gly-Asp, RGD) peptide and a ligand for radioactive isotope labeling are each covalently bonded to amines on both sides of 2,2′-diaminobiphenyl. Moreover, provided are a compound which is for radiopharmaceutical products and to which a radioisotope is bound to the compound, a method for producing the compound for radiopharmaceutical products, and a radiopharmaceutical product containing the compound for radiopharmaceutical products.
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