(2E,4E)-5-PHENYL-PENTA-2,4-DIENE-1-ONE DERIVATIVES

摘要

The present application relates to a novel pentadieonyl compound and a pharmaceutical composition comprising the same. A pentadieonyl compound of the present application inhibits intracellular adipogenesis and fat accumulation within cells and activates fat metabolism, thereby being able to be used for preventing or treating fatty liver and diseases associated with fatty liver. In addition, the pentadieonyl compound of the present application increases the expression of SIRT1 or increases the activity of SIRT1 within cells, thereby being able to be used for preventing or treating diseases associated with SIRT1. Furthermore, the pentadieonyl compound of the present application decreases the expression of CK2 or the activity of CK2 within cells, thereby being able to be used for preventing or treating diseases associated with CK2.;COPYRIGHT KIPO 2020