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Use of anti-CTLA-4 antibodies with enhanced ADCC to enhance immune response to vaccines
Use of anti-CTLA-4 antibodies with enhanced ADCC to enhance immune response to vaccines
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机译:具有增强的ADCC的抗CTLA-4抗体在增强疫苗免疫反应中的应用
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摘要
The present invention provides a method of enhancing an immune response to a vaccine using variant forms of anti-CTLA-4 antibodies with enhanced ADCC activity. Variant anti-CTLA-4 antibodies for use in the present invention include nonfucosylated ipilimumab.
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