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Use of an anti-CTLA-4 antibody with enhanced ADCC to enhance the immune response to a vaccine
Use of an anti-CTLA-4 antibody with enhanced ADCC to enhance the immune response to a vaccine
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机译:具有增强的ADCC的抗CTLA-4抗体在增强针对疫苗的免疫反应中的用途
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摘要
The present invention provides a method for enhancing an immune response to a vaccine using a variant form of an anti-CTLA-4 antibody having enhanced ADCC activity. Variant anti-CTLA-4 antibodies for use in the present invention include non-fucosylated ipilimumab.
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