METHODS FOR DETECTING NUCLEIC ACID SEQUENCE VARIATIONS AND A DEVICE FOR DETECTING NUCLEIC ACID SEQUENCE VARIATIONS USING THE SAME

摘要

The present invention relates to a method for detecting a nucleotide sequence of a target sample, comprising the steps of: obtaining a base sequence of a target sample using a next-generation sequencing method; matching the base sequence of the reference sample with the base sequence of the target sample; A step of selecting a locus that is inconsistent with the sequence and a step of determining a nucleotide sequence variation candidate among loci inconsistent with the error-corrected mutation-probability calculation method according to the type of mutation of the nucleotide sequence, Detection method.