首页> 外国专利> 1-BENZYL-3-HYDROXYMETHYLINDAZOLE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF DISEASES BASED ON THE EXPRESSION OF MCP-1, CX3CR1 AND P40

1-BENZYL-3-HYDROXYMETHYLINDAZOLE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF DISEASES BASED ON THE EXPRESSION OF MCP-1, CX3CR1 AND P40

机译:基于MCP-1,CX3CR1和P40表达的1-苄基-3-羟甲基吲唑衍生物及其在疾病治疗中的应用

摘要

The present invention relates to novel 1-benzyl-3-hydroxymethylindazole derivatives according to Formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present invention relates to the use of 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of a pharmaceutical composition that is active in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40, and to their use in a method for treating or preventing diseases based on the expression of MCP-1, CX3CR1 and p40.
机译:本发明涉及权利要求中所述的根据式(I)的新型1-苄基-3-羟基甲基吲唑衍生物,以及包含它们和可药用载体的药物组合物。另外,本发明涉及1-苄基-3-羟基甲基吲唑衍生物在制备药物组合物中的用途,所述药物组合物基于MCP-1,CX3CR1和p40的表达在疾病治疗中具有活性。用于基于MCP-1,CX3CR1和p40表达的疾病的治疗或预防方法。

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