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METHOD FOR THE SYNTHESIS OF DNA CONJUGATES BY MICELLAR CATALYSIS

机译:胶束催化合成DNA缀合物的方法

摘要

The present invention relates to a compound library comprising a plurality of conjugate molecules, wherein said conjugates comprise a small organic molecule covalently coupled to a nucleic acid moiety, wherein the nucleic acid moiety consists of pyrimidine nucleotides and the plurality of conjugates differ from each other at least by comprising different organic molecules. Further, the present invention relates to the use of said library for screening compounds binding to a target molecule and methods of synthesizing said library.
机译:本发明涉及包含多个缀合物分子的化合物文库,其中所述缀合物包含与核酸部分共价偶联的有机小分子,其中所述核酸部分由嘧啶核苷酸组成,并且所述多个缀合物彼此不同。至少通过包含不同的有机分子。此外,本发明涉及所述文库用于筛选与靶分子结合的化合物的用途和合成所述文库的方法。

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