Oral preparation of glucokinase activator and method for producing the same

摘要

The present invention relates to a solid dispersion containing a glucokinase activator, an isotope-labeled product thereof or a pharmaceutically acceptable salt thereof, and a polymer carrier, and a method for producing the same. Further, the present invention relates to a solid dispersion composition containing the solid dispersion and an excipient. The present invention also relates to an oral formulation of a glucokinase activator containing the solid dispersion or solid dispersion composition. The present invention also relates to glucokinase activator tablets, capsules, and methods for producing the same. The present invention also provides a solid dispersion for the treatment and / or prevention of one or more diseases and diseases selected from the group consisting of type I diabetes, type II diabetes, impaired glucose tolerance, impaired fasting glucose, and hyperglycemia. Use of the body, solid dispersion compositions, and oral formulations including tablets and capsules. [Selection diagram] Fig. 6