首页> 外国专利> Process for obtaining a system for the controlled delivery of a biologically active substance and controlled delivery system obtained thereby

Process for obtaining a system for the controlled delivery of a biologically active substance and controlled delivery system obtained thereby

机译:获得用于控制递送生物活性物质的系统的方法和由此获得的控制递送系统

摘要

The present invention relates to a process for obtaining a system for the controlled delivery of a biologically active substance allowing to obtain an effective delivery in terms of percentage of said biologically active substance that is absorbed by the organism. More particularly, the present invention relates to a process consisting in obtaining a controlled delivery system in which the biologically active substance is enclosed in a structure having a substantially parallelepiped shape with the desired shape and size, which can internally adapt to the biologically active substance to be carried and externally to the interaction with target cells (for example, enterocytes), thus optimizing the delivery modes of said biologically active substance. Advantageously, the process according to the invention allows to create parallelepiped structures with nanometric, micrometric or larger sizes, thereby making the controlled delivery system thus obtained suitable for a large variety of biologically active substances, including ions, molecules and macromolecules.
机译:本发明涉及一种用于获得用于控制地递送生物活性物质的系统的方法,该系统允许以被生物体吸收的所述生物活性物质的百分比来获得有效的递送。更具体地,本发明涉及一种方法,该方法包括获得受控的递送系统,其中将生物活性物质包封在具有所需形状和大小的大致平行六面体形状的结构中,该结构可以在内部适应于生物活性物质以达到所需的目的。与靶细胞(例如,肠上皮细胞)的相互作用被携带在外部并在外部进行,从而优化了所述生物活性物质的递送方式。有利地,根据本发明的方法允许产生具有纳米级,微米级或更大尺寸的平行六面体结构,从而使得如此获得的受控递送系统适合于多种生物活性物质,包括离子,分子和大分子。

著录项

  • 公开/公告号US10517837B2

    专利类型

  • 公开/公告日2019-12-31

    原文格式PDF

  • 申请/专利权人 SUNTEKNA SAGL;

    申请/专利号US201615548963

  • 发明设计人 JOHN KUSTER;

    申请日2016-02-02

  • 分类号A61K9/70;A61K47/36;

  • 国家 US

  • 入库时间 2022-08-21 11:27:37

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