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BIFLAVONE-IRON COMPLEX, PREPARATION METHOD AND APPLICATION THEREOF

机译:双黄酮铁络合物,制备方法及其应用

摘要

A method for preparing a biflavone-iron complex, includes using the amentoflavone as the ligand and the ferric ion as the central ion, the amentoflavone-iron complex is obtained by reaction, and the structure of the complex is characterized by infrared spectroscopy, UV-vis absorption spectroscopy and high resolution mass spectrometry. Meanwhile, the antitumor and antioxidant activities of the amentoflavone-iron complex are studied in the present invention. MTT method shows that the amentoflavone-iron complex has a relatively good antitumor activity, and the antitumor activity thereof is stronger than that of the amentoflavone. Pyrogallol auto-oxidation method and ABTS method show that the antioxidative activity of the amentoflavone-iron complex is stronger than that of the amentoflavone itself.
机译:一种双黄酮-铁配合物的制备方法,包括以黄酮为配体,三价铁离子为中心离子,通过反应得到黄酮-铁配合物,并通过红外光谱,UV-可见吸收光谱和高分辨率质谱。同时,在本发明中研究了黄酮-铁配合物的抗肿瘤和抗氧化活性。 MTT法表明,黄酮-铁配合物具有相对较好的抗肿瘤活性,其抗肿瘤活性强于黄酮。邻苯三酚自氧化法和ABTS法表明,黄酮-铁配合物的抗氧化活性强于黄酮本身。

著录项

  • 公开/公告号US2020239506A1

    专利类型

  • 公开/公告日2020-07-30

    原文格式PDF

  • 申请/专利权人 NANJING FORESTRY UNIVERSITY;

    申请/专利号US201816487848

  • 发明设计人 LI XU;FULIANG CAO;SHILONG YANG;

    申请日2018-02-13

  • 分类号C07F15/02;A61P39/06;

  • 国家 US

  • 入库时间 2022-08-21 11:22:33

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