CHARACTERIZATION OF THE ORAL MICROBIOME FOR THE NON-INVASIVE DIAGNOSIS OF BARRETT'S ESOPHAGUS

摘要

The present invention relates to noninvasive microbiome analyses of Barrett's esophagus (BE) patients in which changes in the relative abundance of certain bacteria indicate a disease likelihood or pathogenic state. Additional aspects of the present invention relate to manipulating the microbiome to treat or prevent BE and related conditions. Embodiments also include monitoring for development of disease or monitoring treatment for prevention or elimination of disease states.