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PATIENT-SPECIFIC LOCAL FIELD POTENTIAL MODEL

机译:患者特定的局部电位模型

摘要

Embodiments discussed herein facilitate identification of a target area within a region of a brain for stimulation via one or more BS (Brain Stimulation) electrodes. One example embodiment comprises generating, based on radiological imaging of a region of a brain of a patient and BS electrode lead(s), a patient-specific anatomical model of the region and lead(s); populating the patient-specific anatomical model with neuron models based on associated neuronal densities of at least one of the region or one or more sub-regions of the region; constructing a patient-specific local field potential (LFP) model of the region based on the patient-specific anatomical model and location(s)/orientation(s) of the one or more BS electrode leads; and identifying, via the patient-specific LFP model of the region, a target area within the region for at least one of monitoring or treatment of a medical condition via the one or more BS electrode leads.
机译:本文讨论的实施例有助于识别大脑区域内的目标区域,以经由一个或多个BS(脑刺激)电极进行刺激。一个示例实施例包括基于患者的脑部区域和BS电极引线的放射学成像,生成该区域和引线的患者特定的解剖模型。基于该区域中至少一个或该区域的一个或多个子区域的相关神经元密度,用神经元模型填充患者特定的解剖模型;基于患者特定的解剖模型和一根或多根BS电极引线的位置/方向,构建区域的患者特定的局部场电势(LFP)模型;通过该区域的患者特定的LFP模型,识别该区域内的目标区域,以通过一根或多根BS电极引线监视或治疗医疗状况中的至少一项。

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