embedded image ;wherein, X is NO3− or Cl−. A method of preparing the biflavone-copper complex includes the following steps: dissolving a copper salt in an alcohol and then adding into a biflavone alcoholic solution, controlling pH to 5-7; under heating and stirring, performing a reaction for 2-5 h to form a precipitate; filtering the precipitate, washing the precipitate with alcohol and water, recrystallizing the precipitate using dimethyl sulfoxide as a solvent, and drying the precipitate to obtain the biflavone-copper complex. The biflavone-copper complex is used for preparing an antitumor drug and/or an antioxidant drug."/> BIFLAVONE-COPPER COMPLEX, PREPARATION METHOD AND APPLICATION THEREOF
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BIFLAVONE-COPPER COMPLEX, PREPARATION METHOD AND APPLICATION THEREOF

机译:双黄酮铜络合物,制备方法及其应用

摘要

A biflavone-copper complex, a preparation method and application thereof are disclosed. The biflavone-copper complex has the following structural formula:; embedded image ;wherein, X is NO3− or Cl−. A method of preparing the biflavone-copper complex includes the following steps: dissolving a copper salt in an alcohol and then adding into a biflavone alcoholic solution, controlling pH to 5-7; under heating and stirring, performing a reaction for 2-5 h to form a precipitate; filtering the precipitate, washing the precipitate with alcohol and water, recrystallizing the precipitate using dimethyl sulfoxide as a solvent, and drying the precipitate to obtain the biflavone-copper complex. The biflavone-copper complex is used for preparing an antitumor drug and/or an antioxidant drug.
机译:公开了一种双黄酮-铜络合物,其制备方法和应用。双黄酮-铜配合物具有以下结构式: “嵌入式图像” ;其中X是NO 3 − 或Cl − 。一种制备双黄酮-铜配合物的方法包括以下步骤:将铜盐溶解在醇中,然后加入双黄酮醇溶液中,控制pH至5-7。在加热搅拌下,反应2-5小时,形成沉淀。过滤沉淀物,用乙醇和水洗涤沉淀物,使用二甲基亚砜作为溶剂使沉淀物重结晶,并将沉淀物干燥以获得双黄酮-铜络合物。双黄酮-铜复合物用于制备抗肿瘤药和/或抗氧化剂。

著录项

  • 公开/公告号US2020010483A1

    专利类型

  • 公开/公告日2020-01-09

    原文格式PDF

  • 申请/专利权人 NANJING FORESTRY UNIVERSITY;

    申请/专利号US201816487845

  • 发明设计人 LI XU;SHILONG YANG;ZHONG LI;

    申请日2018-02-13

  • 分类号C07F1;

  • 国家 US

  • 入库时间 2022-08-21 11:19:33

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