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7-azaindole derivatives as selective type-11-beta-hydroxysteroid dehydrogenase inhibitors
7-azaindole derivatives as selective type-11-beta-hydroxysteroid dehydrogenase inhibitors
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机译:7-氮杂吲哚衍生物作为选择性的11-β-羟基类固醇脱氢酶抑制剂
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摘要
7-azaindole derivatives as selective type-11-beta-hydroxysteroid dehydrogenase inhibitors the present invention relates to 7-azaindole derivatives of formula (i) as selective inhibitors of the type 11-beta-hydroxysteroid dehydrogenase (11beta- hsd-1) and the use of such compounds for the treatment and prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions .
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