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USE OF AN ADRENAL HORMONE-MODIFYING AGENT

机译:肾上腺激素修饰剂的使用

摘要

The present invention relates to a method of treating a disease or disorder characterised by increased stress hormone levels and/or decreased androgen hormone levels in a subject, comprising administering to the subject a therapeutically effective amount of a compound represented by formula (I):wherein n is 1 or 3; R is hydrogen or --C(O)N(R)(R) wherein Rand Rare independently--(C-C) alkyl, or --(C-C) alkyl-(C-C) aryl, wherein each of Rand Ris optionally substituted by --(C-C) alkoxy; RRand Rare independently hydrogen, halogen, cyano or --(C-C) aryl, wherein said --(C-C) aryl is optionally substituted by halogen, with the proviso that no more than one of RRand Ris hydrogen; and Rand Rare hydrogen; or a pharmaceutically acceptable salt thereof.
机译:本发明涉及一种治疗以受试者的应激激素水平升高和/或雄激素水平降低为特征的疾病或病症的方法,其包括向所述受试者施用治疗有效量的由式(I)表示的化合物: n为1或3; R为氢或-C(O)N(R)(R),其中Rand R独立地为-(CC)烷基或-(CC)烷基-(CC)芳基,其中每个Rand Ris任选地被-取代-(CC)烷氧基; RR和R独立地为氢,卤素,氰基或-(C-C)芳基,其中所述-(C-C)芳基任选地被卤素取代,条件是RR和R 1不为氢。和兰德稀有氢;或其药学上可接受的盐。

著录项

  • 公开/公告号HUS2000018I1

    专利类型

  • 公开/公告日2020-07-28

    原文格式PDF

  • 申请/专利权人 RECORDATI AG;

    申请/专利号HUS2000018C

  • 发明设计人

    申请日2020-06-23

  • 分类号

  • 国家 HU

  • 入库时间 2022-08-21 11:17:20

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