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Stable pharmaceutical composition of clopidogrel free base for oral and parenteral administration
Stable pharmaceutical composition of clopidogrel free base for oral and parenteral administration
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机译:用于口服和肠胃外给药的氯吡格雷游离碱的稳定药物组合物
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摘要
The present disclosure provides ready-to-use, oil/water emulsion compositions with mean droplet size (intensity-average, nm) of 100-500 nm, where the oil phase comprises clopidogrel free base dispersed in pharmaceutical acceptable oil(s). The emulsion uses clopidogrel free base or premix of clopidogrel free base in oil(s) as the starting materials and may also contain one or more excipients such as surfactant and or co-surfactant, osmotic agent, pH adjustment agent, antioxidant, preservative, sweetener, and/or suspending agent, etc.
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