DETERMINING POTENTIAL CANCER THERAPEUTIC TARGETS BY JOINT MODELING OF SURVIVAL EVENTS

摘要

A computer-implemented method for determining potential cancer gene therapy targets by joint modeling of cancer survival events comprises employing, by a device operatively coupled to a processor, a multi-task learning model to determine active genetic factors respectively associated with different types of cancer based on cancer survival data and patient genomic data for groups of patients that respectively survived the different types of cancer. The computer-implemented method further comprises determining, by the device, common active genetic factors of the active genetic factors that are shared between two or more types of cancer of the different types of cancer.