The present disclosure relates to a novel composition of antimicrobial and procoagulant agents and methods of using the composition for inhibiting and treating microbial growth at wound sites, inhibiting and treating microbial infections (e.g., bacterial, fungal, viral, parasitic) at wound sites, modulating excessive local and endemic immune reaction, inhibiting microbial infections in biofilms at wound sites, downregulating initial microbial infection at wound sites, preventing cell lysis associated with microbial biofilms at wound sites, inactivating bacterial toxins at wound sites, skin and mucous membranes, preventing the loss of injured extremities, preventing septic shock, reducing superficial bleeding from wounds, promoting tissue regeneration, and promoting the healing of wounds.
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