Pharmaceutical composition for preventing or treating a Malignant Neoplasms Of Breast comprising --epigallocatechin gallate derivatives

摘要

The present invention relates to a pharmaceutical composition for preventing or treating breast cancer comprising an epigallocatechin gallate derivative, wherein the EGCG derivative represented by Formula 1 according to the present invention regulates the expression of uPA and PAI-1 proteins, and ERK1. Pharmaceutical composition for the prevention or treatment of breast cancer because it is effective in inhibiting breast cancer cell metastasis by reducing phosphorylation of / 2 and regulating the expression of p38-MAPK, and also inhibiting the proliferation, infiltration and migration of cancer cells. This can be useful.