Salt of cetagliptin and preparation method thereof, pharmaceutical composition, use

摘要

The present invention provides salts of compounds of formula (I), (I) The salt is a crystalline or amorphous phosphate, or a crystalline or amorphous oxalate. In particular, the phosphate Form B of the present invention has high crystallinity, low hygroscopicity and excellent stability, and the phosphate Form B has excellent oral bioavailability and durability when long-term dosing, and does not easily induce hypoglycemia, and at the same time, has a serum DPPIV inhibitory effect. great.