A clade 2.3.4.4B H5 A Recombinant Influenza A virus and Vaccine Composition for H5 Serotype Influenza A virus belonging to clade 2.3.4.4B comprising the same

摘要

The present invention provides a vaccine composition for a recombinant influenza A virus, a method for manufacturing the same, and an H5 serotype influenza A virus belonging to clade 2.3.4.4B including the same. The present invention may contribute to disease control through a protective effect against a H5 serotype highly pathogenic avian influenza outbreak, which is introduced from overseas or occurs in Korea, by preparing a genetic recombinant vaccine showing a protective effect on a highly pathogenic avian influenza virus. In addition, the vaccine composition is excellent in pathogenicity and safety, as well as the high pathogenicity of the HA segment is removed, and is excellent in proliferation in eggs (egg) and defense in chickens.