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Recombinant Influenza A virus and Vaccine Composition for H5 Serotype Influenza A virus belonging to clade 2.3.4.4B comprising the same
Recombinant Influenza A virus and Vaccine Composition for H5 Serotype Influenza A virus belonging to clade 2.3.4.4B comprising the same
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机译:重组A型流感病毒和属于进化枝2.3.4.4B的H5型A型流感病毒的疫苗组合物
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摘要
The present invention provides a vaccine composition for a recombinant influenza A virus, a method for manufacturing the same, and an H5 serotype influenza A virus belonging to clade 2.3.4.4B including the same. The present invention may contribute to disease control through a protective effect against a H5 serotype highly pathogenic avian influenza outbreak, which is introduced from overseas or occurs in Korea, by preparing a genetic recombinant vaccine showing a protective effect on a highly pathogenic avian influenza virus. In addition, the vaccine composition is excellent in pathogenicity and safety, as well as the high pathogenicity of the HA segment is removed, and is excellent in proliferation in eggs (egg) and defense in chickens.
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