首页> 外国专利> Heterocyclyl-substituted oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors

Heterocyclyl-substituted oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors

机译:杂环取代的恶二唑并吡啶衍生物用作生长素释放肽O-酰基转移酶(GOAT)抑制剂

摘要

The present invention relates to compounds of formula (I). [Formula I] In Formula I, The variables X, R 1 , n, p and q are as defined in claim 1 and have valuable pharmacological properties, in particular, binding to ghrelin O-acyl transferase (GOAT) and regulating its activity. . The compounds are suitable for the treatment and prevention of diseases that may be affected by the receptors, for example metabolic diseases, especially obesity.
机译:本发明涉及式(I)的化合物。 [式I]在式I中,变量X,R 1 ,n,p和q如权利要求1所定义,并且具有有价值的药理特性,特别是与生长素释放肽O-酰基转移酶的结合(山羊)并调节其活动。 。该化合物适用于治疗和预防可能受受体影响的疾病,例如代谢性疾病,特别是肥胖症。

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