首页> 外国专利> HETEROCYCLYL-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS

HETEROCYCLYL-SUBSTITUTED OXADIAZOLOPYRIDINE DERIVATIVES FOR USE AS GHRELIN O-ACYL TRANSFERASE (GOAT) INHIBITORS

机译:杂酚基取代的恶二唑烷基吡啶衍生物,用作生长素释放肽抑制剂(山羊)的O-酰基转移酶(山羊)抑制剂

摘要

The present invention relates to compounds of general formula (I) wherein the variables X, R1, n, p and q are defined as in claim 1, which have valuable pharmacological properties, in particular bind to ghrelin O-acyl transferase (GOAT) and modulate its activity. The compounds are suitable for treatment and prevention of diseases which can be influenced by this receptor, such as metabolic diseases, in particular obesity.
机译:本发明涉及通式(I)的化合物,其中变量X,R 1,n,p和q如权利要求1所定义,其具有有价值的药理特性,特别是与生长素释放肽O-酰基转移酶(GOAT)结合。调节其活动。该化合物适用于治疗和预防可能受该受体影响的疾病,例如代谢疾病,特别是肥胖症。

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