ORAL PHARMACEUTICAL COMPOSITIONS OF DABIGATRAN ETEXILATE

摘要

a) particles of the first type comprise dabigatran itexylate in the form of a freebase or in the form of their pharmaceutically acceptable salts, polymorphs, solvates or hydrates, b) of the second type Particles comprising at least one pharmaceutically acceptable organic acid, a composition comprising a mixture of at least two types of particles, a reduced risk of stroke and tissue embolism and / or selective prosthesis in non-valvular atrial fibrillation patients Use of the composition for the prevention of venous thromboembolism in adult patients who have undergone total hip arthroplasty or total knee arthroplasty, and a process for preparing the composition.