Animal model of schizophrenia using cocaine administration and manufacturing method thereof

摘要

The present invention comprises the steps of administering cocaine to an animal other than a human, a method of manufacturing a schizophrenia animal model, a schizophrenia animal model prepared by the above method, and a screening method of a schizophrenia therapeutic agent using the schizophrenia animal model. It is about. The schizophrenia animal model produced by the method for manufacturing an schizophrenia animal model of the present invention simultaneously shows positive symptoms, negative symptoms, and cognitive symptoms of schizophrenia, and can be used in a short period of time, so it can be used for schizophrenia research and screening treatment for schizophrenia drugs You can.