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A frightening view on schizophrenia. Combining fear conditioning and ketamine administration to investigate emotional blunting in an animal model of schizophrenia

机译：关于精神分裂症的一个令人恐惧的观点。结合恐惧调节和氯胺酮给药研究精神分裂症动物模型中的情绪钝化

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De negatieve symptomen van schizofrenie zijn gerelateerd aan het leren en verwerken van emoties zoals angst. Promovenda Charmaine Pietersen onderzocht of deze emoties nog geleerd en verwerkt kunnen worden bij een (sterk) verminderde functie van het glutamaterge neurotransmitter systeem in de hersenen. De resultaten van het onderzoek ondersteunen eerdere hypotheses over de negatieve symptomen van schizofrenie.

机译：精神分裂症的消极症状与学习和处理情绪（如焦虑症）有关。博士候选人Charmaine Pietersen调查了这些情绪是否仍能通过脑中谷氨酸能神经递质系统的（严重）功能降低而得以学习和处理。研究结果支持有关精神分裂症阴性症状的先前假设。

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Pietersen Charmaine;
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年度 2006
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1. Neuroleptic Drugs Revert the Contextual Fear Conditioning Deficit Presented by Spontaneously Hypertensive Rats: A Potential Animal Model of Emotional Context Processing in Schizophrenia? [J] . Mariana Bendlin Calzavara2 Wladimir Agostini Medrano2 Raquel Levin2 Sonia Regina Kameda2 Monica Levy Andersen3 Sergio Tufik3 Regina Helena Silva4 Roberto Frussa-Filho2 and Vanessa Costhek Abílio12 Schizophrenia Bulletin . 2009,第4期

机译：抗精神病药能逆转自发性高血压大鼠的情境恐惧调节缺陷：精神分裂症情绪情境处理的潜在动物模型吗？
2. Neuroleptic drugs revert the contextual fear conditioning deficit presented by spontaneously hypertensive rats: a potential animal model of emotional context processing in schizophrenia? [J] . Calzavara MB, Medrano WA, Levin R Schizophrenia bulletin . 2009,第4期

机译：抗精神病药能逆转自发性高血压大鼠表现出的情境恐惧调节缺陷：精神分裂症中情绪情境处理的潜在动物模型吗？
3. Comparison of the effects of acute and chronic administration of ketamine on hippocampal oscillations: relevance for the NMDA receptor hypofunction model of schizophrenia. [J] . Kara Kittelberger, Elizabeth E Hur, Saba Sazegar, Brain structure & function . 2012,第2期

机译：氯胺酮急，慢性给药对海马振荡的影响比较：与精神分裂症的NMDA受体功能减退模型相关。
4. Improving Students Learning Outcome Using Group Investigation Model Combined with Think Pair Share and Course Review Horay [C] . Mohammad Dani Wahyudi, Galuh Tripuspitaningrum International Conference on Creativity, Innovation, and Technology in Education . 2019

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5. Effects of clozapine and alprazolam on cognitive deficits and anxiety-like behaviors in a ketamine-induced rat model of schizophrenia. [D] . Phillips, Jennifer M. 2005

机译：氯氮平和阿普唑仑对氯胺酮诱导的精神分裂症大鼠模型认知缺损和焦虑样行为的影响。
6. Neuroleptic Drugs Revert the Contextual Fear Conditioning Deficit Presented by Spontaneously Hypertensive Rats: A Potential Animal Model of Emotional Context Processing in Schizophrenia? [O] . Mariana Bendlin Calzavara, Wladimir Agostini Medrano, Raquel Levin, 2009

机译：抗精神病药能逆转自发性高血压大鼠的情境恐惧调节缺陷：精神分裂症情绪情境处理的潜在动物模型吗？
7. An animal model of emotional blunting in schizophrenia. [O] . Charmaine Y Pietersen, Fokko J Bosker, Janine Doorduin, 2007

机译：精神分裂症情绪钝化的动物模型。
8. Corticosterone Administration to Promote Fear Memory Forgetting Process in an Animal Model of PTSD [R] . Li, H., Zhang, L., Ursano, R. J., 2010

机译：皮质酮给药促进创伤后应激障碍动物模型中的恐惧记忆遗忘过程

A frightening view on schizophrenia. Combining fear conditioning and ketamine administration to investigate emotional blunting in an animal model of schizophrenia

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