首页> 外国专利> Compound for inducing the degradation of cereblon protein preparation method thereof and pharmaceutical composition for use in preventing or treating cancer containing the same as an active ingredient

Compound for inducing the degradation of cereblon protein preparation method thereof and pharmaceutical composition for use in preventing or treating cancer containing the same as an active ingredient

机译:诱导脑神经蛋白质降解的化合物及其制备方法和用于预防或治疗癌症的药物组合物

摘要

The present invention relates to a pharmaceutical composition for the prevention or treatment of cancer containing a compound for inducing the decomposition of a cerebron protein, a preparation method thereof, and an active ingredient thereof, to A-Linker-A or A-Linker-B according to the present invention The new compounds displayed can inhibit or decompose the cerebrone excellently, and contain it as an active ingredient to achieve an effect such as treatment, prevention or improvement from inhibiting or decomposing a cerebrone-related disease, preferably cerebrone. It has a useful effect as a pharmaceutical composition for the prevention or treatment of diseases that can be, for example, cancer, autoimmune diseases, or metabolic diseases.
机译:本发明涉及一种用于预防或治疗癌症的药物组合物,其包含用于诱导脑神经蛋白分解的化合物,其制备方法及其活性成分,其涉及A-Linker-A或A-Linker-B。根据本发明,所展示的新化合物可以极好地抑制或分解脑神经素,并含有其作为活性成分,以达到诸如治疗,预防或改善抑制或分解脑神经素相关疾病,优选脑神经素的作用。它作为用于预防或治疗例如癌症,自身免疫疾病或代谢性疾病的疾病的药物组合物具有有用的作用。

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