UTILISATION D'UN COMPOSÉ DE FERRUGININE A (FGA) EN TANT QU'AGENT ET CHIMIOTHÉRAPIQUE ET INHITEUR DE LA VOIE MAPK EN RAISON DE SON ACTIVITÉ BIOLOGIQUE

摘要

The invention relates to use ferruginin A (FGA) compound that presents an effective cytotoxic activity in cancer chemotherapy as an anticancer agent and MAPK pathway inhibitor. The objective of the invention is to use Ferruginin A (FGA) compound that can be isolated from the bark of Harungana madagascariensis, as an anticancer agent and as MAPK pathway inhibitor at MCF-7 cells. The fact that Ferruginin A presents low effect on human normal skin fibroblasts, thus presents selective toxicity towards the cancer cells selective toxicity is exploited under the scope of the invention.