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神经疾病的治疗及记忆力减退改善用生药组合物

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摘要

本发明涉及一种包含龙眼肉、丹参及天麻提取物作为有效成分的神经疾病的预防或治疗用组合物。本发明的神经疾病预防组合物在对使直接参与认知功能障碍的神经递质即乙酰胆碱减少的乙酰胆碱酯酶的活性进行抑制时起到优秀的作用。并且，本发明的组合物将已证明生物体安全性的龙眼肉、丹参及天麻提取物作为有效成分来利用，因而对人体非常安全。

著录项

公开/公告号CN109568499A

专利类型发明专利
公开/公告日2019-04-05

原文格式PDF
申请/专利权人百疗医株式会社;
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申请/专利号CN201811127563.1
发明设计人李头奭;金东植;金善嬉;
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申请日2012-03-29
分类号A61K36/8988(20060101);A61K36/9066(20060101);A61P25/28(20060101);A61P25/14(20060101);A61P25/16(20060101);A61P25/00(20060101);A61P21/00(20060101);A61P25/24(20060101);A61P25/18(20060101);A61P39/02(20060101);A23L33/105(20160101);
代理机构11038 中国国际贸易促进委员会专利商标事务所;
代理人谭玮
地址韩国首尔
入库时间 2024-02-19 07:11:44

法律信息

法律状态公告日

法律状态信息

法律状态
2019-08-06

著录事项变更 IPC(主分类):A61K36/8988 变更前: 变更后: 申请日:20120329

著录事项变更
2019-07-12

著录事项变更 IPC(主分类):A61K36/8988 变更前: 变更后: 申请日:20120329

著录事项变更
2019-04-30

实质审查的生效 IPC(主分类):A61K36/8988 申请日:20120329

实质审查的生效
2019-04-05

公开

公开

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1. 神经疾病的治疗及记忆力减退改善用生药组合物 [P] . 中国专利： CN109568499A . 2019-04-05
2. 神经疾病的治疗及记忆力减退改善用生药组合物 [P] . 中国专利： CN103533948A . 2014-01-22
3. compound, process for preparing same, pharmaceutical composition, methods for inhibiting dipeptidyl peptidase-iv, for treating conditions mediated by inhibition of dipeptidyl peptidase-iv, increased islet neogenesis, b-cell survival, and insulin biosynthesis in a mammalian patient, and a disease or condition, to treat, control, or prevent diabetes, hyperglycemia, obesity, insulin resistance, one or more disorders, atherosclerosis, one or more conditions in a mammalian patient, neutropenia, and anemia, to treat or control growth hormone deficiency and hiv infection in a mammalian patient, modulate the immune response in a mammalian patient, reduce sperm motility, and produce a pharmaceutical composition, and, pharmaceutical combination [P] . BRPI0416444A . 2007-02-27

机译：化合物，其制备方法，药物组合物，抑制二肽基肽酶-iv的方法，用于治疗由抑制二肽基肽酶-iv介导的疾病，提高的胰岛新生，b细胞存活和胰岛素生物合成的疾病的患者治疗或控制糖尿病，高血糖，肥胖，胰岛素抵抗，一种或多种疾病，动脉粥样硬化，哺乳动物患者的一种或多种疾病，中性粒细胞减少和贫血的一种或多种疾病，以治疗或控制生长激素缺乏症和艾滋病毒感染在哺乳动物患者中，调节哺乳动物患者的免疫反应，减少精子运动，并产生药物组合物，以及药物组合
4. spirocyclic heterocyclic compound, pharmaceutical composition, method to bind opioid receptors, methods to prevent or treat pain, gastrointestinal dysfunction, a urogenital tract disorder, an immunomodulatory disorder, an inflammatory disorder, a respiratory function disorder, anxiety, mood disorder, a stress-related disorder, sympathetic nervous system disorder, cough, and a motor disorder, method for treating traumatic injury to the central nervous system, methods for preventing or treating stroke, cardiac arrhythmia, glaucoma, and sexual dysfunction, methods for treating a condition selected from the group consisting of shock, cerebral edema, cerebral ischemia, cerebral deficit after cardiac surgery (bypass) and graft, systemic lupus erythematosus, hodgkin's disease, sjogren's disease, epilepsy, and rejection in organ transplants and skin grafts, and to treat substance dependence, method to improve organ and cell survival, and cardioprotection after myocardial infarction, methods to [P] . BRPI0415165A . 2007-01-09

机译：螺环杂环化合物，药物组合物，阿片受体的结合方法，预防或治疗疼痛，胃肠道功能障碍，泌尿生殖道疾病，免疫调节疾病，炎性疾病，呼吸功能疾病，焦虑症，情绪障碍，与压力有关的方法疾病，交感神经系统疾病，咳嗽和运动障碍，治疗中枢神经系统创伤的方法，预防或治疗中风，心律不齐，青光眼和性功能障碍的方法，治疗选自以下组的疾病的方法包括休克，脑水肿，脑缺血，心脏手术（旁路）和移植后脑缺损，系统性红斑狼疮，霍奇金病，干燥综合征，癫痫和器官移植和皮肤移植排斥反应，以及治疗药物依赖的方法改善器官和细胞存活率以及心肌梗死后的心脏保护作用，
5. compound of formula i; pharmaceutical composition; method of treating disorders that are related to or affected by inhibition of norepinephrine reuptake, the 5-ht6 receptor or the 5-ht2a receptor; a method of treating a learning disorder, a cognitive disorder, a memory disorder, a personality disorder, a behavioral disorder, a movement disorder, a neurodegenerative disorder, drug withdrawal disorder, sleep, an eating disorder, acute drug toxicity, a cardiovascular disorder, a sexual dysfunction, a gastrointestinal disorder, a genitourinary disorder, a pain disorder, a nervous disorder or a symptom disorder vasomotor; method of treating alzheimer's disease, attention deficit disorder, schizophrenia, parkinson's disease, tardive dyskinesia, ataxia, bradykinesia, paroxysmal dyskinesias, restless leg syndrome, tremor, essential tremor epilepsy, stroke or head trauma; method of treating coronary artery disease, myocardial infarction, transient ischemic attack, angina, atrial fibrillation, p [P] . BRPI0706523A2 . 2011-01-04

机译：式I化合物;药物组合物;治疗与去甲肾上腺素再摄取，5-ht6受体或5-ht2a受体相关或受其抑制的疾病的方法;一种治疗学习障碍，认知障碍，记忆障碍，人格障碍，行为障碍，运动障碍，神经退行性疾病，戒断药物，睡眠，进食障碍，急性药物毒性，心血管疾病的方法，性功能障碍，胃肠道疾病，泌尿生殖系统疾病，疼痛疾病，神经疾病或症状-血管舒缩;治疗阿尔茨海默氏病，注意力缺陷障碍，精神分裂症，帕金森氏病，迟发性运动障碍，共济失调，运动迟缓，阵发性运动障碍，不安腿综合征，震颤，原发性震颤癫痫，中风或头部外伤的方法;治疗冠状动脉疾病，心肌梗塞，短暂性脑缺血发作，心绞痛，心房颤动，p的方法