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Technical Refinement of Hepatic Vein Reconstruction in Living Donor Liver Transplantation Using Left Liver Graft

机译:左肝移植肝活体肝移植术中肝静脉重建的技术改进

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摘要

Background: In adult living donor liver transplantation (LDLT), left liver graft is generally safer for the donor. The aim of this study was to demonstrate a technical refinement for achieving sufficient outflow using left liver graft. Material/Methods: Forty-seven cases using left liver were divided into 2 groups according to the procedures of hepatic vein reconstruction: the side-clamp group (21 cases), and the cross-clamp group (26 cases), to sufficiently enlarge the diameter of the hepatic vein with excising the inferior vena cava (IVC). Results: The liver function tests at 7 days after LDLT were not significantly different between the 2 groups, but the median amount of ascites was significantly greater in the side-clamp group (1250 ml; range, 484–3690) than in the cross-clamp group (582 ml; 190–2785). When we selected the patients with the ratio of graft weight to recipient standard liver volume less than 30%, the 1-year patient survival after transplantation was significantly better in the cross-clamp group than in the side-clamp group (90% in cross-clamp group vs. 71% in side-clamp group, P>0.05). Conclusions: In conclusion, hepatic vein reconstruction with cross-clamping of the IVC can secure a sufficient outflow in LDLT using left liver graft.
机译:背景:在成人活体供体肝移植(LDLT)中,左肝移植物通常对供体更安全。这项研究的目的是证明使用左肝移植物实现足够流出的技术改进。资料/方法:根据肝静脉重建手术方法,将四十七例左肝患者分为两组:侧钳组(21例)和交叉钳组(26例),以充分扩大切除下腔静脉(IVC)的肝静脉直径。结果:LDLT后7天的肝功能测试在两组之间无显着差异,但侧钳组(1250 ml;范围484–3690)的腹水中位数明显高于交叉固定组。钳组(582毫升; 190–2785)。当我们选择移植物重量与受体标准肝体积之比小于30%的患者时,交叉夹钳组的移植后1年患者生存率明显好于侧面夹钳组(90%钳组,侧面钳组为71%,P> 0.05)。结论:总之,使用左肝移植物通过IVC交叉钳夹进行肝静脉重建可以确保LDLT充分流出。

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