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Mild cognitive impairment and dementia in a heterogeneous elderly population: prevalence and risk profile

机译:在异质性老年人群中轻度认知障碍和痴呆:患病率和风险状况

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摘要

OBJECTIVE:To describe the demographic, clinical and risk profile of Mild Cognitive Impairment and dementia in a sample of elderly South Africans within a residential setting.METHOD:One hundred and forty participants residing in a group of residential homes for the elderly were assessed by psychiatrists and assigned diagnoses of dementia or Mild Cognitive Impairment (MCI). Participants diagnosed with dementia were also offered haematological investigations and a CT scan of the brain.RESULTS:The sample consisted of 140 participants comprising 46.4% White, 29.3% Coloured, 20% Asian and 4.3% Black participants. There were 97 (69.3%) females and 106 (75.7%) participants had less than 12 years of education. Eleven (7.9%) dementia and 38 (27.1%) MCI cases were diagnosed. Increasing age was associated with cognitive impairment (MCI and dementia) (p=.020) but there was no association between gender and cognitive impairment (p=.165). MCI was significantly associated with a lower education level (p=.036) and no association was found between depression (current-p=.646; past-p=.719) and dementia or MCI. The presence of vascular risk factors (n=140) ranged from 66.4% (hypertension) to 14.3% (stroke). Subjective memory complaints were significantly associated with cognitive impairment (p=.001). Except for the use of the telephone (p=.225) and the television (p=.08), impairment in all domains of instrumental activities of daily living that were assessed were significantly associated with a dementia diagnosis.CONCLUSION:The study showed that cognitive impairment was associated with increasing age and low education levels. The presence of vascular risk factors places this population at risk for future cognitive decline.
机译:目的:描述在居住环境中的南非老年人样本中的轻度认知障碍和痴呆症的人口统计学,临床和风险特征。方法:由精神科医生评估居住在一组老年人住宅中的一百四十名参与者并分配了痴呆或轻度认知障碍(MCI)诊断。结果:该样本由140名参与者组成,包括46.4%的白人,29.3%的有色人种,20%的亚洲人和4.3%的黑人参与者。有97名(69.3%)女性和106名(75.7%)参与者受过不到12年的教育。诊断出11例(7.9%)痴呆症和38例(27.1%)MCI病例。年龄增长与认知障碍(MCI和痴呆)相关(p = .020),但性别与认知障碍之间没有关联(p = .165)。 MCI与低学历水平显着相关(p = .036),并且在抑郁症(当前-p = .646;过去-p = .719)与痴呆或MCI之间没有关联。血管危险因素(n = 140)的存在范围从66.4%(高血压)到14.3%(中风)。主观记忆障碍与认知障碍显着相关(p = .001)。除了使用电话(p = .225)和电视(p = .08)以外,评估的日常生活中工具活动的所有领域的障碍都与痴呆症诊断显着相关。结论:该研究表明认知障碍与年龄增长和低文化程度有关。血管危险因素的存在使该人群面临未来认知能力下降的风险。

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