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Analytical modeling of carbon nanotube transistor based biosensor for glucose detection

机译:用于碳检测的基于碳纳米管晶体管的生物传感器的分析模型

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摘要

The industry in sensory devices, nowadays, has become overflowed with the development of carbon nanotubes based sensor. So far, wide ranges of potential and practical applications of CNTs have been reported, including chemical sensors electronic devices and so on. CNT possess enhanced electron transfer property when used as electrodes in electrochemical reactions and serves as a good solid support for easy protein immobilization that retains their native activity for use as potential biosensors. The determination of glucose levels using biosensors, particularly in the medical diagnostics and food industries, is gaining mass appeal. The glucose biosensors detect the glucose molecule by catalyzing glucose to the gluconic acid and H2O2 in the presence of oxygen. In this study, a single-wall carbon nanotube field-effect transistor (SWCNT FET) biosensor for glucose detection is analytically modelled. In the proposed model, the glucose concentration is presented as a function of gate voltage. Subsequently, the proposed model is compared with existing experimental data. A good consensus between the model and the experimental data is reported. The simulated data demonstrate that the analytical model can be employed with an electrochemical glucose sensor to predict the behavior of the sensing mechanism in biosensors.
机译:如今,随着基于碳纳米管的传感器的发展,传感设备行业已经泛滥成灾。迄今为止,已经报道了碳纳米管的广泛的潜在和实际应用,包括化学传感器电子设备等。 CNT在电化学反应中用作电极时,具有增强的电子转移性能,并作为易于固定蛋白质的良好固体支持物,保留了其天然活性,可用作潜在的生物传感器。使用生物传感器来确定葡萄糖水平,尤其是在医学诊断和食品工业中,正在引起人们的广泛关注。葡萄糖生物传感器通过在氧气存在下将葡萄糖催化为葡萄糖酸和H2O2来检测葡萄糖分子。在这项研究中,对葡萄糖检测的单壁碳纳米管场效应晶体管(SWCNT FET)生物传感器进行了建模。在提出的模型中,葡萄糖浓度表示为栅极电压的函数。随后,将提出的模型与现有的实验数据进行比较。报告了模型与实验数据之间的良好共识。仿真数据表明,该分析模型可与电化学葡萄糖传感器一起使用,以预测生物传感器中传感机制的行为。

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    Hosseingholipourasl Ali;

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  • 年度 2014
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  • 原文格式 PDF
  • 正文语种 en
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