Intraocular tissue migration of silicone oil after silicone oil tamponade: A histopathological study of enucleated silicone oil-filled eyes

摘要

Retrospective clinical and histopathological review of eightsilicone oil-filled enucleated eyeballs using light microscopywas carried out in our department of ocular pathology duringa period of six years. In all cases, silicone oil vacuoles, both freeand incorporated within macrophages were seen in all the retinallayers. Silicone oil vacuoles were seen in the optic nerve, choroid,retinal pigment epithelium, corneal stroma, iris and ciliary bodystroma, preretinal and subretinal membranes and retro-cornealmembranes. Silicone oil migration could be seen in intraoculartissues as early as two months post surgery. There was no definitehistopathological correlation between duration of tamponadeand distribution of silicone oil vacuoles. Silicone oil vacuoleswere seen in the optic nerve in eyes with neovascular glaucoma.Chronic inflammatory reaction was observed in the retinal tissuein the vicinity of silicone oil vacuoles.