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Evaluating the suitability of Hydrobia ulvae as a test species for sediment metal toxicity testing applying a tissue residue approach to metal mixtures in laboratory and field exposures

机译:通过组织残留法对实验室和现场暴露中的金属混合物进行组织残留评估,评估水bia的适宜性作为沉积金属毒性测试的测试物种

摘要

A major weakness in evaluating the suitability of a biomonitor organism is the poor ability to predict the variability of the bioavailability of metals from measured environmental concentrations. In this study, the intertidal gastropod Hydrobia ulvae was used to evaluate its suitability as a test organism for assessing sediment metal toxicity. Toxicity tests were run with sediments spiked with copper, cadmium and zinc applied both as single metal and as a mixture to investigate toxicological interactions evaluating different lethal and sublethal effects. Dose-response relationships were constructed based both on tissue residue approach and particulate metal concentrations. Because metal-spiked sediments used in routine toxicity tests often do not exhibit the same adsorption/desorption kinetics as the natural sediments, the laboratory results were compared to 10-d bioassays conducted with natural field sediments collected from the Guadalete estuary (SW Spain). Highly significant correlations between tissue residue concentrations and particulate metal concentrations were found for all metal-spiked or field-collected and demonstrated that: (i) H. ulvae readily accumulated copper and cadmium in response to contamination and (ii) dietary uptake was determined to be the most significant route of metal exposure. The comparison of the modeled tissue residue-response curve developed from the mixture tests was in good agreement with the results from the bioassay conducted with field sediments and strongly demonstrated that H. ulvae is also a suitable test organism for assessing copper sediment toxicity. In contrast, the dose-response curve expressed as a function of total particulate metal concentrations would fail in predicting effect, erroneously assessing higher metal toxicity. © 2013 Elsevier Ltd.
机译:评估生物监控生物的适用性的主要弱点是根据测量的环境浓度预测金属的生物利用度变异性的能力较弱。在这项研究中,潮间带腹足纲水Hydro被用来评估其是否适合作为评估沉积物金属毒性的测试生物。对沉积物掺以铜,镉和锌作为单一金属和混合物形式进行的毒性试验,以研究毒理学相互作用,评估不同的致死和亚致死作用。基于组织残留法和金属微粒浓度建立剂量-反应关系。由于常规毒性测试中使用的金属掺入沉积物通常不表现出与天然沉积物相同的吸附/解吸动力学,因此将实验室结果与从瓜达莱特河口(西班牙西班牙)收集的天然田间沉积物进行的10天生物测定进行了比较。发现所有金属加标或田间采集的组织残留物浓度与金属微粒浓度之间具有高度显着的相关性,并证明:(i)腐霉菌因污染而易于积聚铜和镉,并且(ii)确定饮食摄入是最重要的金属暴露途径。通过混合试验建立的模型组织残留-响应曲线的比较与对田间沉积物进行生物测定的结果非常吻合,并强烈证明了汉逊酵母也是评估铜沉积物毒性的合适试验生物。相反,表示为总颗粒金属浓度的函数的剂量反应曲线将无法预测效果,从而错误地评估了较高的金属毒性。 ©2013爱思唯尔有限公司。

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