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Modeling and Analysis of SOI Gratings-Based Opto-Fluidic Biosensor for Lab-on-a-Chip Applications

机译:基于SOI光栅的光流体生物传感器对实验室应用的建模与分析

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摘要

The design, modeling, and analysis of a silicon-on-insulator (SOI) grating coupler integrated with a microfluidic channel for lab-on-a-chip applications are presented. The grating coupler was designed to operate at 1310 nm. The simulated SOI structure consisted of a 220 nm top-Si device layer with an integrated waveguide, grating coupler, and a buried oxide layer of 2 µm. A rectangular microfluidic channel was deposited on the SOI optical grating structure for light and fluid interaction. The fluidic flow through the device was driven by centrifugal and Coriolis forces. The grating structure was designed to achieve a maximum coupling efficiency at the optimized injection angle of the light source. The sensitivity of the grating structure could be analyzed and evaluated using the change in coupled power as a function of the effective refractive index and was found to be 0.928 × 10−6 RIU. The SOI optical grating structure along with the micro fluidic channel on top could be effectively used as an absorbance-based lab-on-a-chip biosensor.
机译:提供了与微流体通道集成的绝缘体(SOI)光栅耦合器的设计,建模和分析,用于实验室应用的实验室应用。光栅耦合器设计成在1310nm处运行。模拟的SOI结构由220nm顶-Si器件层组成,具有集成的波导,光栅耦合器和2μm的掩埋氧化物层。沉积在SOI光学光栅结构上的矩形微流体通道,用于光和流体相互作用。通过该装置的流体流动由离心和科里奥利力驱动。光栅结构被设计为在光源的优化注射角度实现最大耦合效率。使用耦合功率的变化作为有效折射率的函数,可以分析和评估光栅结构的灵敏度,并被发现为0.928×10-6的RIU。 SOI光学光栅结构与顶部的微流体通道一起有效地用作基于吸光度的实验室的芯片生物传感器。

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