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Mediterranean Diet in patients with acute ischemic stroke: Relationships between Mediterranean Diet score, diagnostic subtype, and stroke severity index

机译:急性缺血性卒中患者的地中海饮食:地中海饮食评分,诊断亚型和中风严重程度指数之间的关系

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摘要

Background: Adherence to a Mediterranean Diet appears to reduce the risk of cardiovascular disease, cancer, Alzheimer's disease, and Parkinson's disease, as well as the risk of death due to cardiovascular disease. No study has addressed the association between diagnostic subtype of stroke and its severity and adherence to a Mediterranean Diet in subjects with acute ischemic stroke. Aim: To evaluate the association between Mediterranean Diet adherence, TOAST subtype, and stroke severity by means of a retrospective study. Methods: The type of acute ischemic stroke was classified according to the TOAST criteria. All patients admitted to our ward with acute ischemic stroke completed a 137-item validated food-frequency questionnaire adapted to the Sicilian population. A scale indicating the degree of adherence to the traditional Mediterranean Diet was used (Me-Di score: range 0-9). Results: 198 subjects with acute ischemic stroke and 100 control subjects without stroke. Stroke subjects had a lower mean Mediterranean Diet score compared to 100 controls without stroke. We observed a significant positive correlation between Me-Di score and SSS score, whereas we observed a negative relationship between Me-Di score and NIHSS and Rankin scores. Subjects with atherosclerotic (LAAS) stroke subtype had a lower mean Me-Di score compared to subjects with other subtypes. Multinomial logistic regression analysis in a simple model showed a negative relationship between MeDi score and LAAS subtype vs. lacunar subtype (and LAAS vs. cardio-embolic subtype). Conclusions: Patients with lower adherence to a Mediterranean Diet are more likely to have an atherosclerotic (LAAS) stroke, a worse clinical presentation of ischemic stroke at admission and a higher Rankin score at discharge.
机译:背景:遵守地中海饮食似乎降低了心血管疾病,癌症,阿尔茨海默病和帕金森病的风险,以及由于心血管疾病导致的死亡风险。没有研究已经解决了脑卒中诊断亚型与其严重程度与急性缺血性卒中的受试者中的地中海饮食之间的关联。目的:通过回顾性研究评估地中海饮食粘附,吐司亚型和冲程严重程度之间的关联。方法:根据吐司标准对急性缺血性卒中的类型进行分类。所有患者患有急性缺血中风的患者都完成了一个137项验证的食物频率调查问卷,适应西西里人群。使用表明遵守传统地中海饮食的程度(Me-DI得分:0-9)。结果:198名受急性缺血性卒中的受试者和100个没有中风的受试者。中风受试者具有较低的平均饮食分数与100个没有中风的控制。我们观察到ME-DI分数和SSS分数之间的显着正相关,而我们观察到ME-DI分数和NIHSS和RANKIN评分之间的负面关系。与带有其他亚型的受试者相比,具有动脉粥样硬化(LaAs)中风亚型的受试者具有较低的平均值。一种简单模型中的多项逻辑回归分析显示了MEDI评分与LaAS亚型与Levunar亚型(和LaAS与Cardio-栓塞亚型)之间的负面关系。结论:对地中海饮食较低的患者更有可能具有动脉粥样硬化(LAAS)中风,在入院时更糟糕的缺血性卒中的临床介绍,并且在放电时较高的Rankin得分。

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