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The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase

机译：5-取代的哌嗪作为一种新型二级药程，大大提高了可溶性环氧化物水解酶的尿素的抑制剂的物理性质

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Hui-Yuan Li; Yi Jin; Christophe Morisseau; Bruce D. Hammock; Ya-Qiu Long;
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1. The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase. [J] . Li HY, Jin Y, Morisseau C, Bioorganic and medicinal chemistry . 2006,第19期

机译：5-取代的哌嗪作为新型的第二药效基团，极大地改善了基于尿素的可溶性环氧化物水解酶抑制剂的物理性能。
2. The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase. [J] . Li HY, Jin Y, Morisseau C, Bioorganic and Medicinal Chemistry . 2006,第19期

机译：5-取代的哌嗪作为新型的第二药效基团，极大地改善了基于尿素的可溶性环氧化物水解酶抑制剂的物理性能。
3. Incorporation of piperazino functionality into 1,3-disubstituted urea as the tertiary pharmacophore affording potent inhibitors of soluble epoxide hydrolase with improved pharmacokinetic properties [J] . Huang S.-X., Li H.-Y., Liu J.-Y., Journal of Medicinal Chemistry . 2010,第23期

机译：将哌嗪子基官能团掺入1,3-二取代的尿素中作为第三级药效团，可提供有效的可溶性环氧化物水解酶抑制剂，并具有改善的药代动力学特性
4. PHYSICAL SOLUBILITY AND DIFFUSIVITY OF N2O AND CO2 IN AQUEOUS 2-AMINO-2-METHYL~(-1)-PROPANOL BLENDED WITH PIPERAZINE SOLUTION [C] . Won-Joon Choi, Sang-Sup Lee, Jong-Beom Seo American Chemical Society National Meeting . 2007

机译：用哌嗪溶液混合2-氨基-2-甲基水 - 氨基-2-甲基水溶液中N 2 O和CO 2的物理溶解度和扩散性
5. Beneficial Effects of Soluble Epoxide Hydrolase Inhibitors in Cardiovascular Diseases: Insight Gained Using Metabolomic Approaches. [D] . Li, Ning. 2011

机译：可溶性环氧水解酶抑制剂在心血管疾病中的有益作用：通过代谢组学方法获得的见识。
6. The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase [O] . Hui-Yuan Li, Yi Jin, Christophe Morisseau, -1

机译：5-取代的哌嗪作为新型的第二药效基团极大地改善了基于尿素的可溶性环氧化物水解酶抑制剂的物理性能
7. 1,3-Disubstituted Ureas Functionalized with Ether Groups are Potent Inhibitors of the Soluble Epoxide Hydrolase with Improved Pharmacokinetic Properties [O] . In-hae Kim, Hsing-ju Tsai, Kosuke Nishi, 2015

机译：用醚基官能化的1,3-二取代脲是可溶性环氧化物水解酶的有效抑制剂，具有改善的药代动力学特性

The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase

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