In vitro analysis of nanoparticles released from polyamide nanomaterialcomposites during drilling process

摘要

Nanomaterials provide a new avenue of progress into technological development.By manipulating materials on the very basic atomic and molecular levels theproperty of a given material can be specifically altered to suit the purpose ofintended applications. However, nanomaterials (nanoparticles and nanolayers)have a more complex nature in physiochemical properties and surface reactivitythan their larger counterparts. Therefore, the release of these nanomaterials asdust during crushing or drilling may lead to serious health hazards for humansand the surrounding environment. This study, supported by the NEPHH(Nanomaterial-related Environmental Pollution Health Hazards), addresses twoimportant questions about nanomaterials: - Whether nanomaterials can be releasedfrom physical process of nanoproducts. - Toxicity potential of nanodustsgenerated from nanoproducts in comparison with reference products. Bothquestions address a massive gap in knowledge for toxicity and more specificallynanomaterial toxicity.