User's Guide for the Integrated Exposure Uptake Biokinetic Model for Lead in Children (IEUBK) Windows (Trade Name).

摘要

The Integrated Exposure Uptake Biokinetic Model for Lead (Pb) in Children, Windows (IEUBKwin)is a stand-alone personal computer (PC)-compatible software package. The model utilizes four interrelated modules (exposure, uptake, biokinetic, and probability distribution) to estimate blood lead (PbB) levels in children exposed to lead (Pb)-contaminated media. IEUBKwin allows the user to estimate, for a hypothetical child or population of children, a plausible distribution of PbB concent-rations centered on a geometric mean PbB concentration. The geometric mean PbB is predicted from available information about the childs or childrens exposure to lead. From this distribution, the model estimates the risk (i.e., probability) that a childs or a population of childrens PbB concentration will exceed a certain level of concern (typically 10 mu g/dL).