Understanding Dermal Exposure: A Critical Step in Exposure Assessment.

摘要

The skin is a major target for chemical exposure via contact with aerosols, vapors, liquids, contaminated soils, or other contaminated surfaces. The importance of dermal exposure has become more evident as inhalation exposure decreases as a result of improved preventative/ personal protection measures. The extent and significance of dermal exposure remain largely unknown, primarily because there is a lack of standard instruments and methods for measuring chemical-specific dermal exposure. Methods are not only needed to quantify exposure, but to also evaluate the relationship of dermal exposure to systemic exposure.